Understanding alcohol metabolism products: The problem with too much NADH
Alcohol metabolism produces excess amounts of NADH (Nicotinamide Adenine Dinucleotide plus Hydrogen). This excess of NADH can lead to acidosis from lactic acid build-up and hypoglycemia from lack of glucose synthesis. It can also lead to weight gain, fatty liver, and heart attack. Realistically, these are not simple health conditions to be taken lightly. And because of that, besides understanding alcohol metabolism products, doctor Dalal Akoury made a decision of creating AWAREmed health and wellness resource center with the primary objective of transforming each individual’s life through increasing awareness about health and wellness and by empowering individuals to find their own inner healing power. It will further interest you to note that, doctor Akoury’s practice focuses on personalized medicine through healthy lifestyle choices that deal with primary prevention and underlying causes instead of patching up symptoms making her the best among the best for your treatment consideration. You may want to call her on telephone number 843 213 1480 to book an appointment at your convenience, in the meantime, let’s look at how alcohol is affecting people differently.
Understanding alcohol metabolism products: Alcohol affects some people differently from others
Women – If a woman and a man of the same weight drink the same amount of alcohol under the exact same circumstances, the woman will on the average have a much higher BAC (Blood Alcohol Content) than the man. This is because women have much less of the enzyme alcohol dehydrogenase in their stomachs than men do. If the same man and woman are given an injection of alcohol instead of drinking it they will tend to have the same BAC. This is because when the alcohol is injected it bypasses the alcohol dehydrogenase in the stomach.
Older Males – As men age they tend to produce less alcohol dehydrogenase. Older men are likely to become more intoxicated on smaller amounts of alcohol than younger men. Alcohol dehydrogenase in women is apparently not affected by age.
Menopausal Women – Apparently hormone changes which occur at menopause can cause menopausal women to become more intoxicated on smaller doses of alcohol.
People with Liver Damage – People with liver damage produce less alcohol dehydrogenase than do those with healthy livers and thus can become more intoxicated on smaller doses of alcohol. This phenomenon is referred to as Reverse Tolerance.
Frequent Heavy Drinkers – Frequent heavy drinkers produce more alcohol dehydrogenase than other people and thus become less intoxicated on larger quantities of alcohol. These people can metabolize up to 38 ml (over 2 standard drinks) of alcohol per hour whereas the average person metabolizes only around 13 ml (about 0.7 standard drinks) per hour.
East Asians and American Indians
Most individuals use a form of acetaldehyde dehydrogenase called ALD2 to metabolize the acetaldehyde which results from alcohol metabolism. However, many East Asians and American Indians produce a form of acetaldehyde dehydrogenase called ALD2*2 which is far less efficient at breaking down acetaldehyde than ALD2. ALD2*2 is only about 8% as efficient as ALD2 at metabolizing acetaldehyde.
Understanding alcohol metabolism products: The problem with too much NADH
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