Inflammation Control to Slow Premature Aging – Mechanisms of Inflammation in Aging

In our desire to keep the beautiful skin that everyone will admire, we are consistently faced with several challenges. Some of the challengers can be very devastating and will require the professionals to be involved if permanent solution is to be found. For this reason, we are going to be consulting with doctor Dalal Akoury from time to time as we progress into the discussion about calming chronic inflammation and slow premature aging. Just for the record, doctor Akoury is one of the few professionals with more than two decades experience in beauty and skincare management. She is also the founder of a health facility known as AWAREmed Health and Wellness Resource Center where we focus is on Neuroendocrine Restoration (NER) to reinstate normality through realization of the oneness of Spirit, Mind, and Body, Unifying the threesome into ONE.

With that brief introduction, let’s get into the discussion. Chronic inflammation can destructively affect your health and even accelerate your skin’s aging. Therefore inflammation is a critical part of the body’s healing process: It occurs at the cellular level when the immune system tries to fight off disease causing germs and repair injured tissue. Inflammation can be invisible (if your body is battling an infection internally) or visible: Rashes or pimples, for example, occur when blood vessels widen near the skin’s surface to increase blood flow, which in turn expedites healing.

Redness, heat and swelling can also occur alongside inflammation. When the fight is over, the army of inflammation-triggering substances is supposed to withdraw, however in many cases they don’t. Besides that studies have implicated chronic inflammation with heart disease, diabetes, cancer and many more of such diseases. When it attacks the skin, it can accelerate fine lines, wrinkles and enlarged pores, as well as puffiness, sagging, blotchiness or reddening of the skin. All this impacts negatively on the health of the skin and the end result is premature aging. Therefore aging is a progressive degenerative process tightly integrated with inflammation. However the cause and effect are not very clear though a number of theories have been developed that attempt to define the role of chronic inflammation in aging including:

• Redox stress
• Mitochondrial damage
• Immune-senescence
• Endocrino-senescence
• Epigenetic modifications and
• Age-related diseases

We are going to discuss each of this aspects as we progress on but nonetheless, no single theory explains all aspects of aging, it is likely that multiple processes contribute and that all are entangled with inflammatory responses. Take for example human immunodeficiency virus (HIV)-infected individuals experiences premature aging phenomenon this may provide indicators to better explain the nature of inflammation in aging. Environmental and lifestyle effectors of inflammation may also contribute to variation of both inflammation and age-related dysfunction.

Inflammation Control to Slow Premature Aging – Inflammation and Aging

It must be noted that aging itself is not a disease. However it results from the accumulation over time of detrimental changes at the molecular and cellular levels, and ultimately at the level of tissues and organs, resulting in disease and increased risk of morbidity and mortality. Traditionally, robust immune and inflammatory responses allowed early humans to endure to reproductive age. However, these same response mechanisms lead to a variety of lethal consequences now that humans routinely endure to older age. In a highly elaborate process, organs lose functionality and structural integrity both deriving from and leading to age-related diseases like atherosclerosis, dementia, and cancer. While the etiology of the aging process is not fully understood, inflammation clearly plays a major role, inseparably linking inflammation and aging.

Nonetheless it is not clear whether inflammation causes age-related processes, results from these processes or both. For the purpose of this article we will concentrate on current theories about the nature of chronic inflammation associated with aging including the causes and effects of inflammation with a focus on the highly entangled nature of aging and inflammation and potential interventions to moderate the effects of inflammation in aging.

Inflammation Control to Slow Premature Aging – Chronic Inflammation

Subsequent to trauma or infection, the inflammatory response is initiated at a local, cellular level. A number of cellular mediators such as macrophages and monocytes are activated. These cells release cytokines like tumor necrosis factor-α and interleukin-6 which act as molecular mediators and are responsible for the progression of the response to a systemic level encompassing multiple organs. The inflammatory cascade is designed to:

• Destroy microbial pathogens
• Initiate tissue repair processes and
• Promote a return to physiological homeostasis

Remember that at an acute level, this process is marked by easily discernible heat, swelling, redness, and pain. However, in terms of aging and age-related diseases, the inflammation response is a chronic, low level, subclinical process mediated by the same effectors, but opposing significantly in degree Inflammation as a function of age has been well characterized in numerous epidemiologic studies. Levels of inflammatory mediators typically increase with age even in the absence of acute infection or other physiologic stress. While levels are still in the sub-acute range, this chronic inflammation underlies many aging-related conditions. However, a key question remains. Is inflammation a cause of the aging process or an effect? We are going to be answering this question in our next article when we handle Mechanisms of Inflammation in Aging. You don’t want to miss this and so I asked you to stay on the link for a while as we unlock the truth about inflammation.

Meanwhile as I had mention in the introduction, this is not just any topic about healthcare. We are looking at the real issues that bring about premature aging. If you want to remain young even if you’re not, engage the experts at AWAREmed Health and Wellness Resource Center under the able leadership of Doctor Akoury’s care. Schedule for that appointment today and get to know your position with the effects of inflammation. You may never know until you get the experts opinion. It doesn’t matter where you are or what you do, our concern is to help you keep that glamorous appearance for a very long time. Give us an opportunity to help you keep that youthful look by calling doctor Akoury today.

Inflammation Control to Slow Premature Aging – Mechanisms of Inflammation in Aging