Cellular body inflammation causes obesity: Health complications attached
A common theme that links many diseases and chronic illness is uncontrolled cellular body inflammation. It is a factor with most diseases including cardiovascular disease, diabetes, cancer, arthritis and many autoimmune-related conditions. And from the expert desk at AWAREmed health and wellness resource center under the leadership of doctor Dalal Akoury MD, it will interest you to note that recently obesity has recently been added to this group of diseases because it is equally presenting a low grade inflammatory response within many of the body’s tissues, which cause deleterious effects leading to the development of cardiovascular and metabolic disease.
It is well known that being overweight is detrimental to one’s health, but until recently the known mechanisms were limited. Scientists over the last decade have started to unravel the mystery of why obesity leads to premature death. Although there is still much to learn, it is valuable to comprehend the known effects of chronic inflammation, as the prevalence of obesity continues to be a rising problem among the American population, particularly in children.
Cellular body inflammation causes obesity: Chronic Inflammation
Inflammation is, by design, a protective response leading to the repair of tissue. When inflammation becomes chronic, as is the case with obesity, chemical mediators, derived from different cellular activities, change in dynamics causing a progressive state of decline. Fat cells are now considered an immune organ that secretes numerous immune modulating chemicals. Visceral fat, in particular, is associated with the low grade inflammation that seems to be a contributing pathologic feature for metabolic disease through insulin resistance and the promotion of atherosclerotic build-up in circulatory vessels.
When high levels of visceral fat are combined with physical inactivity, over nutrition, and advancement in age, the effect becomes more pronounced. Visceral fat is highly metabolic and contributes to cytokine hyperactivity. Adipokines secreted from fat tissue influence the metabolic process and contribute to proper function. The consequent low grade inflammation associated with obesity causes disturbance in the secretion and function of adipokines. Research has identified changes in adiponectin, leptin, and resisting that exhibit harmful effects upon the body in obese individuals. Adiponectin is an antiatherogenic agent, meaning it helps prevent the development of atheroschlerotic plaque in blood vessels and slows the progression of atherosclerosis in coronary vessels. It does this by acting directly upon the vessel wall, inhibiting adhesive molecules from contributing to plaque formation and acts as a blocking agent to the formation of foam cells.
Finally, take note that in the skeletal muscle and the liver, adiponectin serves to promote insulin sensitivity and a positive blood lipid profile. Visceral adiposity reduces adiponectin concentrations. Lowering the adiponectin concentrations lessens the cardio protective effect, leading to increased cardiovascular risk. You may have realized that in this discussion of cellular body inflammation and how it causes obesity, a lot of medical terminologies are applied which may not make sense to many lay people. In appreciating that fact and to help you take good precautions about obesity and overweight, we want to encourage you to schedule an appointment with doctor Dalal Akoury not for a one on one simplicity discussions that will address all your concerns and have then addressed professionally.
Cellular body inflammation causes obesity: Health complications attached
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